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Poster

The fibrillar-level mechanisms of mutability in echinoderm connective tissue analysed using in situ synchrotron small-angle X-ray scattering

Sunday (01.01.2040)
00:00 - 21:10
Part of:
Line-Up:
- Poster The versatile usage of wrinkled surfaces 1 Bernhard Alexander Glatz
- Poster Penguin feather mimicking oil infused elastomer for anti-icing property 1 Dipl.-Ing. Nguyen Thanh-Binh
- Poster Radiation-based methods for surface modification of supramolecular peptide fibrils 0 Juhaina Bandak
- Poster Investigation of crack propagation of hierarchically structured ceramic materials on different length scales using bending tests 1 Cecilia Müller
- Poster Tobacco mosaic virus disks, preparation of samples to investigate mineralization by low voltage electron microscopy 1 Dr. Sabine Eiben
- Poster Deformation of Liquid-Liquid Phase Boundary as Template for Novel Surface Structured Polymer Particles and Coatings 1 Helena vom Stein
- Poster Sclerenchymatic tissue in Banksia follicles – The effect of moisture on dimensional and mechanical properties 1 Friedrich Reppe
- Poster Reconstructing in-situ nanofibrillar orientation and mechanics in arthropod cuticle using X-ray diffraction modelling 1 Ph.D. Yanhong Wang
- Poster Structural origins of morphing in plant tissues 1 Prof. Dr. Hanoch Daniel Wagner
- Poster What is the effect of cell network topology on the poro-elastic properties of bone? 1 Alexander van Tol
- Poster The fibrillar-level mechanisms of mutability in echinoderm connective tissue analysed using in situ synchrotron small-angle X-ray scattering 1 Dr. Himadri Shikhar Gupta
- Poster Growing bone-like tissues on negative Gaussian curvature surfaces 1 Prof. Dr. John Dunlop
- Poster Gradient porous materials for reliable structured adhesives 1 Ph.D. Di Tan
- Poster Transfer of surface properties of wheat leaves to technical surfaces 1 Miriam Huth
- Poster Damping Behaviour of Bioinspired and Natural Fibre Composites 1 Wilhelm Woigk
- Poster Cancer cells biomineralize ionic gold into nanoparticles-microplates via secreting defense proteins with specific gold-binding peptides 1 Dr. Ajay Vikram Singh
- Poster Microstructural Assessment of Calvarial Fusion in Mice of Different Ages and its Biomechanical Implications 1 Dr. Junning Chen
- Poster Diffusion-limited electroless silver reduction on copper for "porous monocrystal" 1 Dr. Nikolay Ryzhkov
- Poster Multiscale simulations of directed spider dragline silk self-assembly by flow 1 Dipl.-Ing. Ana Herrera
- Poster Inspirational Multiscale Natural Structures 1 Dr. XiaoMeng Sui
- Poster The Exoskeleton of Scorpions: from Structure to Mechanical Function 1 Israel Kellersztein
- Poster Investigating the multilayer fiber-reinforced structure of the wood cell using computer simulations and additive manufacturing 1 Laura Zorzetto
- Poster Light guided 3D-structuring of EPS produced by red algae 1 Moritz Klotz
- Poster Structural optimization of biopolymer composite Cottonid by variation of manufacturing parameters 1 Matthias Langhansl
- Poster Biomineralization of Materials made of Engineered Spider Silk Proteins 1 Vanessa Wicklein
- Poster Micro-Ikebana by Biomimetic Crystallization of Alkaline Earth Carbonates 1 Shota Kobayashi
- Poster Bioinspired hairy surfaces 0 Stefan Müllers
- Poster Reagent-free modification of bio-hydrogels by electron irradiation towards biomedical applications 1 Stefanie Riedel
- Poster Controlled Modification on Wood via SI-ATRP 1 Marta Vidiella del Blanco
- Poster Plant Biomimetics: Surface-Structured Pollen Particles and Transparent Flower Petals 1 Prof. Dr. Olaf Karthaus
- Poster Coupling of polymers to tobacco mosaic virus: towards the production of amphiphilic virus tubes 1 Dr. Sabine Eiben
- Poster Mechanical stable sulfobetainc Hydrogels - A candidate for biomedical application 1 Ramona Bianca Jasmin Ihlenburg
- Poster Structuring V2O5 Nanocomposites to Adapt the Sponge Spicules’ Architecture 1 Achim Diem
- Poster Fibers, Yarns and Non-Woven Meshes – Tough Morphologies Made of Recombinant Spider Silk Proteins 1 Fabian Müller
- Poster Recombinant Spider Silk-based Hybrid Materials for Advanced Energy Technology 1 Tamara Aigner
- Poster Bio-mediated materials syntheses 1 Dr. Daniel Van Opdenbosch
- Poster Design of Biomimetic Thin Coatings Composed of Cellulose Beta-Nanocrystals for Epitaxial Crystallization and Coassembly of 1D Nanoparticles 0 Dipl.-Ing. Zihao Lu
- Poster Seeded Mineralization Leads to Prismatic-Type CaCO3 Thin Coatings with Multiple Structural Functions 0 Ming Li
- Poster Multifunctional Layered Magnetic Composites 1 Christian Debus
- Poster Cuttlebone-inspired Structures for Mechanical Damping 1 Dipl.-Ing. Andrea Knöller

Session P.1: Poster discussion evening
Belongs to:
Session P: Poster Presentation


The collagenous matrix is a critical biomechanical component of soft structural biological tissues (skin, bone, heart valves) in both vertebrates and invertebrates [1]. However, in contrast to tissues like muscle, most collagenous tissues serve largely passive mechanical roles. A striking exception is the mutable collagenous tissue (MCT) of echinoderms (like sea cucumbers or starfish), which can change its mechanical state from flaccid to stiff within seconds in response to external stimuli such as touch or predatory attack [3]. However, the nanoscale mechanisms enabling mutability have not been investigated experimentally. Here, we used in situ synchrotron small-angle X-ray diffraction (SAXD) to map temporal changes in collagen fibrillar ultrastructure in different mechanical states of MCT from sea cucumber dermis [2]. On application of tensile strain, we find a higher proportion of strain taken up by the fibrils when the tissue is macroscopically stiffened, compared to when it is in the soft state. A staggered model of anisotropic collagen fibrils surrounded by an extrafibrillar matrix of proteoglycans, water and neuroeffector molecules is used to interpret the data. Our results show that mutability alterations in tissue mechanics - concurrent with small-scale fibrillar behaviour – can be explained only if the interfibrillar matrix changes its mechanical state while the collagen fibrils remain mechanically unchanged. Our findings may have applications in design of bioinspired stimuli-responsive hydrogels, linking echinoderm biomechanics to molecular alterations and in testing the efficacy of synthetic peptides for softening or stiffening collagenous tissue.

Speaker:
Dr. Himadri Shikhar Gupta
Queen Mary University of London
Additional Authors:
  • Jingyi Mo
    University of Manchester
  • Dr. Sylvain F. Prevost
    Institut Laue-Langevin
  • Dr. Liisa M. Blowes
    Queen Mary University of London
  • Dr. Michaela Egertova
    Queen Mary University of London
  • Prof. Dr. Nicholas J. Terrill
    Diamond Light Source
  • Prof. Dr. Wen Wang
    Queen Mary University of London
  • Prof. Dr. Maurice R. Elphick
    Queen Mary University of London