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Short Poster Lecture

3D printed PLA scaffolds for the mineralization of calcium phosphate

Monday (19.03.2018)
20:50 - 20:55
Part of:


We described 3D printed poly lactic acid (PLA) bodies as scaffolds for hydrogel-calcium phosphate (CP)-hybrid materials for prospective application as biomaterial.[1] The PLA was given a specific shape using fused deposition modelling (FDM) which in principle allows to create individualized implants for every patient. After the printing process the PLA was surface modified using NaOH and (3-Aminoproypl)-triethoxysilane (APTES). To generate a hydrogel, two different biopolymers, namely gelatin and chitosan, were used and crosslinked with glutaraldehyde. The modified PLA was coated with a hydrogel-CP-hybrid material using an alternating dip coating process. SEM pictures, EDX spectra, and XRD data show a mixture of different calcium phosphates, namely brushite, octacalcium phosphate, and hydroxyapatite.

Currently we are investigating other methods for surface modification e.g. binding of an alkyne function for further chemical modifications and to avoid the usage of APTES. Furthermore other crosslinking agents will be tested instead of glutaraldehyde.

 

Ref. [1] Schneider et al., Polymers, 2017, submitted

Speaker:
Matthias Schneider
University of Potsdam
Additional Authors:
  • Dr. Christina Günter
    University of Potsdam
  • Prof. Dr. Andreas Taubert
    University of Potsdam

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